Anti-Mullerian Hormone (AMH) Fertility Test
The AMH test (Anti-Mullerian Hormone) is a blood test to help the fertility doctors check a woman’s ovarian (Egg) reserve. It’s a test that measures the levels of AMH in a woman’s blood and is helpful in determining whether a woman has premature ovarian aging (diminished ovarian reserve) or premature ovarian failure.
What Is AMH?
The Anti-Mullerian Hormone is a substance secreted by the granulosa cells from the developing eggs or follicles. As a woman grows older, her number of ovarian follicles begins to decrease, therefore, the amount of AMH in the blood decreases.
A woman who has very few remaining follicles will have low AMH levels and is close to menopause. A woman who has many small ovarian follicles — a condition known as polycystic ovarian syndrome (PCOS) — typically has high levels of AMH.
How AMH Is a Predictor of Ovarian Reserve?
Because AMH levels correlate with the number of ovarian follicles, the test is a good predictor of ovarian (egg) reserve. Women with higher concentrations of AMH have a better response to ovarian stimulation and are likely to produce more eggs for IVF (in vitro fertilization) than women with low or undetectable AMH. Also, unlike follicle stimulating hormone (FSH), the levels of AMH in the blood do not fluctuate as much; therefore the test can be done at any point during the menstrual cycle. However, it can be falsely lowered with the prolonged use of birth control pills. If your initial test result is lower than anticipated and you’re taking birth control pills your doctor may suggest you stop the pills for a month and then repeat the test to get a more accurate reading.
A low AMH indicates there is a problem with the quantity and quality of a woman’s eggs. Women with low AMH tend to be “poor responders” to fertility treatment — even with high doses of fertility drugs.
AMH test “normal” AMH range is also dependent upon age — the average AMH level in younger women is higher than the average level in older women. Therefore, a young woman with a very low AMH could have a similar level to an older woman who is considered to have an “average” AMH level for her age. AMH is only one of the tests that assesses ovarian reserve. Others include blood tests for FSH and estradiol levels and a vaginal ultrasound examination of the antral follicles early in a women’s menstrual cycle.
If you’d like to learn more about the Anti-Mullerian Hormone (AHM) Fertility Test, please schedule an appointment at CT Fertility Trumbull, CT to meet with a physician and discuss your options.